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What are the different neurodegenerative diseases?

Several cognitive disorders similar to Alzheimer's disease, grouped under the generic term of related or neurodegenerative diseases, have their own characteristics, even if they have common symptoms.

Here are the main degenerative diseases of the brain:

Little is known about vascular dementia, although it is the second dementia in France in terms of the number of people affected. The neurological disorders observed are due to a cardiovascular accident (stroke), which manifests itself by hemorrhage or embolism of the cerebral vessels. It causes cognitive symptoms, especially in memory

The differential diagnosis of vascular dementia is based on the faculties affected and their potential for recovery. Cognitive losses are often irreversible as with Alzheimer's.

Lewy body disease is the second disease related to Alzheimer's in view of its prevalence: 15 to 20% of dementias. Little known, this pathology is caused by abnormal deposits of “Lewy bodies” in neurons. The average age of onset of DCL is between 50 and 70 years and its progression is faster than that of these pathologies.

The first symptoms are mainly disturbances in attention, with few memory problems.

Then come syncope, falls behind, parkinsonian symptoms, hallucinations ...

The progression to dementia is much faster than with Alzheimer's disease.

Other types of Alzheimer's-related diseases include frontotemporal degeneration, including Pick's disease. This is characterized by the presence of particular cells called “Pick's body”, discovered after autopsy.

These Alzheimer's-like diseases are called FTD because the frontal and sometimes temporal areas of the brain are affected. The lesions cause behavioral and personality disorders:

  • withdrawal into oneself,
  • physical neglect,
  • impulsiveness,
  • vulgarity,
  • excessive anger and susceptibility, and sometimes language disorders.

On the other hand, memory problems are much less important than in Alzheimer's disease.

These related diseases usually appear before the age of 65, but progress over 10 to 15 years. People with FTD retain their autonomy and retain their brain capacities for a long time (thinking, orientation, etc.).

Symptoms of Parkinson's disease appear between the ages of 50 and 70. It affects the brain cells responsible for controlling movement.

There are several forms of temporal lobe atrophy:

  • Primary progressive aphasia: It is characterized by disorders of language and comprehension for about 2 years.
  • Semantic dementia: This is a degenerative disorder characterized by the loss of the meaning of words and objects. The person speaks, but without logic. Over the long term, the evolution of these symptoms can lead to frontal degeneration.

Steele-Richardson disease is a combination of intellectual disorders, symptoms of Parkinson's disease and gaze palsy. Loss of balance, language difficulties, psychomotor slowing are some of them.

This disease related to Alzheimer's attacks more particularly the cortex. It causes paralysis and involuntary contractions of certain muscles similar to those of Parkinson's disease.

Symptoms of Huntington's disease usually start between the ages of 30 and 50. However, this hereditary disease can begin after the age of 50 for the late form. It causes motor, cognitive as well as psychiatric t rubles.

The sporadic form of this cognitive disorder is more common in people aged 70 to 79. It is a neurodegenerative disease that is rarer than other dementias. It causes abnormal muscle movements, memory, mood and vision problems. Its evolution is very fast.

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